- #Calcusyn combination index pdf
- #Calcusyn combination index manual
- #Calcusyn combination index license
- #Calcusyn combination index plus
A comprehensive manual is supplied as.pdf with the software and there is a detailed Help file. There are flexible arrangements for printing of results and graphs and their export to spreadsheets, wordprocessors, graphics packages etc. CalcuSyn Version 2.0 has Undo and Redo tools. All data and results are easily accessible by mouse-click on the contents tree.
The plots drawn by CalcuSyn include dose-effect, median-effect, isobolograms and CI-effect. Estimates of accuracy of EDx and CI can be calculated with Monte Carlo simulations or by a highly accurate algebraic estimation algorithm.
#Calcusyn combination index plus
CalcuSyn automatically graphs the data and produces reports giving summary statistics on all drugs plus detailed analysis of drug interactions including the Combination Index and EDx (for any value of x). Data can be processed both for individual drugs and for constant-ratio or non-constant-ratio combinations of drugs. When the grid is used, data can be processed through wizards which make the software easily accessible to new users. Data can be entered via the keyboard or file import either into the grid or directly into the analysis engine. CalcuSyn can easily be integrated with other software. It performs multiple drug dose-effect calculations using the Median Effect methods described by T-C Chou and P. Mixed drug treatment is becoming common in the treatment of cancer, AIDS etc, and CalcuSyn is the most widely used software for establishing efficacy in this field.
#Calcusyn combination index license
Details on the use of CalcuSyn are found in the software user's manual (14).īiosoft: Software for Science Version 2 US $300, UK £175 * – single user license – online fulfillment Dose-Effect Analyzer for Single and Multiple Drugs CalcuSyn Version 2.0 is the definitive analyzer of combined drug effects, able automatically to quantify phenomena such as synergism and inhibition. See also these computer simulations in pharmacology and physiology.And values for assessing drug interactions described below, CalcuSyn can deter.
#Calcusyn combination index pdf
Price: Single user license: US$300/£175 5 user license: US$900/£525 10 user license: US$1500/£875 (all include a manual as pdf file) An additional charge of US$90/£50 is made for supply of a hard copy (CD) if required. Orders outside the United Kingdom, please click here. A screenshot and a downloadable demo are available here. This program can be ordered online. CalcuSyn is suitable for the study of drug mixtures.Ĭomments & References: Suitable for academic labs and pharmaceutical companies. These give a thorough account of the theoretical basis of the analysis methods including the statistical treatment of results.
A comprehensive manual is supplied with the software and there is a detailed Help file. The plots drawn by CalcuSyn include dose-effect, median-effect, isobolograms and CI-effect. All data and results are easily accessible by mouse-click on the contents tree. CalcuSyn Version 2.0 has Undo and Redo tools. There are flexible arrangements for printing of results and graphs and their export to spreadsheets, wordprocessors, and graphics packages. CalcuSyn automatically graphs the data and produces reports giving summary statistics on all drugs plus detailed analysis of drug interactions including the Combination Index and EDx (for any value of x). Estimates of accuracy of EDx and CI can be calculated with Monte Carlo simulations or by a highly accurate algebraic estimation algorithm. Data can be processed both for individual drugs, and for constant-ratio or non-constant-ratio combinations of drugs. 4, 450-454). CalcuSyn can easily be integrated with other software. CalcuSyn performs multiple drug dose-effect calculations using the Median Effect methods described by T-C Chou and P. CalcuSyn Version 2.0 is the analyzer of combined drug effects, able automatically to quantify phenomena such as synergism and inhibition. The use of combined drug treatments is becoming common in the treatment of cancer and AIDS.